
Polynucleotides in Brussels: The New Generation of Skin Regeneration
What Are Polynucleotides and Why Are They Trending in Aesthetic Medicine?
Aesthetic medicine is increasingly focused on regeneration and skin quality, not just volume. Polynucleotide treatments are gaining attention because they support the skin’s natural repair processes, helping improve hydration, elasticity, and overall texture over time. At House of Glow in Brussels, polynucleotides are used as part of a personalised approach to natural-looking rejuvenation.
What Are Polynucleotides?
Polynucleotides are highly purified DNA fragments used in aesthetic medicine to improve skin quality. Rather than reshaping the face, they help optimise the skin’s biological environment and support a healthier, more resilient complexion.
They are often chosen to help improve:
— skin hydration and glow
— texture and elasticity
— fine lines and crepey skin
— overall skin comfort and resilience

How Do Polynucleotides Work?
Polynucleotides are injected into targeted areas of the skin. They are designed to support tissue repair and stimulate fibroblast activity—processes linked to collagen production and skin renewal. Results develop progressively, with a natural improvement in skin quality over the following weeks.
Why Are They Trending?
Polynucleotides align with what many patients want today:
— subtle, natural-looking results
— treatments that enhance skin quality rather than change facial features
— regenerative, long-term approaches to anti-ageing
— options for delicate areas where volume is not the goal
What Areas Can Be Treated?
Polynucleotides are commonly used for:
— under-eye area
— cheeks
— neck
— décolleté
— fine lines around the mouth
They are especially useful when the main concern is skin texture, hydration, or early laxity.
What Results Can You Expect?
Patients often notice a gradual improvement in:
— hydration and radiance
— smoother texture
— firmer, more elastic skin
Because the treatment supports regeneration, results are progressive and natural rather than immediate or dramatic.
Polynucleotides vs Fillers: What’s the Difference?
— Fillers add volume and can reshape contours.
— Polynucleotides improve skin quality without adding volume.
At House of Glow, they may be recommended alone or combined with other treatments as part of a full facial rejuvenation plan.
Book a Consultation
Ready to glow? Start with a consultation with Dr. Gijsen to assess your needs, explain the treatment, and create a personalised plan for safe, natural results.
Polynucleotides FAQ
Most patients experience minimal discomfort. The injections are very fine, and the treatment is generally well tolerated. A personalised approach ensures your comfort throughout the session.
A course of 2 to 3 sessions is commonly recommended, spaced a few weeks apart. The exact number depends on your skin condition and aesthetic goals.
Side effects are usually mild and temporary, such as slight redness, swelling, or small injection marks. These typically resolve within 24 to 48 hours.
Results develop gradually as the skin regenerates. Most patients notice improved hydration and texture after a few weeks, with continued improvement over time.
Polynucleotides are suitable for most skin types and are especially effective for improving skin quality and hydration. A consultation is essential to confirm the best treatment plan for you.
Results can last several months depending on skin condition and lifestyle. Maintenance sessions may be recommended to prolong and optimise results.




